G291-0147 Screening compound: 4-(morpholin-4-yl)-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carbonitrile

G291-0147 Screening compound: 4-(morpholin-4-yl)-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carbonitrile
G291-0147 Screening compound: 4-(morpholin-4-yl)-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound G291-0147
4-(morpholin-4-yl)-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G291-0147

Molecular Formula

C20H21F3N6O (C20 H21 F3 N6 O)

Compound Name

4-(morpholin-4-yl)-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carbonitrile

IUPAC name

4-(morpholin-4-yl)-6-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyrimidine-5-carbonitrile

SMILES

N#Cc1c(N2CCOCC2)ncnc1N(CC1)CCN1c1cccc(C(F)(F)F)c1

InChI

InChI=1S/C20H21F3N6O/c21-20(22,23)15-2-1-3-16(12-15)27-4-6-28(7-5-27)18-17(13-24)19(26-14-25-18)29-8-10-30-11-9-29/h1-3,12,14H,4-11H2

InChI Key

BVVFOCUJMYHISO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32223581

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.677

Distribution Coefficient, logD

3.677

Water Solubility, LogSw

-4.27

Polar Surface Area

55.044

Acid Dissociation Constant (pKa)

22.92

Base Dissociation Constant (pKb)

1.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

G291-0147 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with G291-0147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G291-0147?
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What is the minimum amount of G291-0147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G291-0147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G291-0147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G291-0147 available by request