G291-0303 Screening compound: 4-[(3,5-dimethylphenyl)amino]-6-(morpholin-4-yl)pyrimidine-5-carbonitrile

G291-0303 Screening compound: 4-[(3,5-dimethylphenyl)amino]-6-(morpholin-4-yl)pyrimidine-5-carbonitrile
G291-0303 Screening compound: 4-[(3,5-dimethylphenyl)amino]-6-(morpholin-4-yl)pyrimidine-5-carbonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound G291-0303
4-[(3,5-dimethylphenyl)amino]-6-(morpholin-4-yl)pyrimidine-5-carbonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G291-0303

Molecular Formula

C17H19N5O (C17 H19 N5 O)

Compound Name

4-[(3,5-dimethylphenyl)amino]-6-(morpholin-4-yl)pyrimidine-5-carbonitrile

IUPAC name

4-[(35-dimethylphenyl)amino]-6-(morpholin-4-yl)pyrimidine-5-carbonitrile

SMILES

Cc1cc(Nc(ncnc2N3CCOCC3)c2C#N)cc(C)c1

InChI

InChI=1S/C17H19N5O/c1-12-7-13(2)9-14(8-12)21-16-15(10-18)17(20-11-19-16)22-3-5-23-6-4-22/h7-9,11H,3-6H2,1-2H3,(H,19,20,21)

InChI Key

DCMWHCXINOCDDY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD32223596

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

309.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.237

Distribution Coefficient, logD

3.237

Water Solubility, LogSw

-3.32

Polar Surface Area

57.951

Acid Dissociation Constant (pKa)

15.32

Base Dissociation Constant (pKb)

3.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.29

G291-0303 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G291-0303 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G291-0303?
Check Price and Availability of G291-0303, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G291-0303 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G291-0303
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G291-0303
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G291-0303 available by request