G307-0221 Screening compound: methyl 4-{2-[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]acetamido}benzoate

G307-0221 Screening compound: methyl 4-{2-[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]acetamido}benzoate
G307-0221 Screening compound: methyl 4-{2-[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G307-0221
methyl 4-{2-[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G307-0221

Molecular Formula

C18H22N4O5S (C18 H22 N4 O5 S)

Compound Name

methyl 4-{2-[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]acetamido}benzoate

IUPAC name

methyl 4-{2-[4-(piperidine-1-sulfonyl)-1H-imidazol-1-yl]acetamido}benzoate

SMILES

COC(c(cc1)ccc1NC(Cn1cnc(S(N2CCCCC2)(=O)=O)c1)=O)=O

InChI

InChI=1S/C18H22N4O5S/c1-27-18(24)14-5-7-15(8-6-14)20-16(23)11-21-12-17(19-13-21)28(25,26)22-9-3-2-4-10-22/h5-8,12-13H,2-4,9-11H2,1H3,(H,20,23)

InChI Key

PVPMCHDRARYEGG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14996443

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.46

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.859

Distribution Coefficient, logD

1.859

Water Solubility, LogSw

-2.54

Polar Surface Area

88.111

Acid Dissociation Constant (pKa)

10.79

Base Dissociation Constant (pKb)

-0.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

G307-0221 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G307-0221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G307-0221?
Check Price and Availability of G307-0221, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G307-0221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G307-0221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G307-0221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G307-0221 available by request