G307-2894 Screening compound: 2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]-N-(4-sulfamoylphenyl)acetamide

G307-2894 Screening compound: 2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]-N-(4-sulfamoylphenyl)acetamide
G307-2894 Screening compound: 2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]-N-(4-sulfamoylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G307-2894
2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]-N-(4-sulfamoylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G307-2894

Molecular Formula

C19H19N5O5S2 (C19 H19 N5 O5 S2)

Compound Name

2-[4-(2,3-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]-N-(4-sulfamoylphenyl)acetamide

IUPAC name

2-[4-(23-dihydro-1H-indole-1-sulfonyl)-1H-imidazol-1-yl]-N-(4-sulfamoylphenyl)acetamide

SMILES

NS(c(cc1)ccc1NC(Cn1cnc(S(N(CC2)c3c2cccc3)(=O)=O)c1)=O)(=O)=O

InChI

InChI=1S/C19H19N5O5S2/c20-30(26,27)16-7-5-15(6-8-16)22-18(25)11-23-12-19(21-13-23)31(28,29)24-10-9-14-3-1-2-4-17(14)24/h1-8,12-13H,9-11H2,(H,22,25)(H2,20,26,27)

InChI Key

SMJRMBMOTVRRDC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14996809

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

461.52

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.845

Distribution Coefficient, logD

0.844

Water Solubility, LogSw

-2.22

Polar Surface Area

117.347

Acid Dissociation Constant (pKa)

10.01

Base Dissociation Constant (pKb)

-0.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

G307-2894 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G307-2894 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G307-2894?
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What is the minimum amount of G307-2894 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G307-2894
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G307-2894
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G307-2894 available by request