G327-1651 Screening compound: N~4~-(1-benzyl-4-piperidyl)-3-(4-chlorophenyl)-1H-pyrazole-4-carboxamide

G327-1651 Screening compound: N~4~-(1-benzyl-4-piperidyl)-3-(4-chlorophenyl)-1H-pyrazole-4-carboxamide
G327-1651 Screening compound: N~4~-(1-benzyl-4-piperidyl)-3-(4-chlorophenyl)-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G327-1651
N~4~-(1-benzyl-4-piperidyl)-3-(4-chlorophenyl)-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G327-1651

Molecular Formula

C22H23ClN4O (C22 H23 ClN4 O)

Compound Name

N~4~-(1-benzyl-4-piperidyl)-3-(4-chlorophenyl)-1H-pyrazole-4-carboxamide

IUPAC name

n/a

SMILES

O=C(c1c[nH]nc1-c(cc1)ccc1Cl)NC1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C22H23ClN4O/c23-18-8-6-17(7-9-18)21-20(14-24-26-21)22(28)25-19-10-12-27(13-11-19)15-16-4-2-1-3-5-16/h1-9,14,19H,10-13,15H2,(H,24,26)(H,25,28)

InChI Key

KXPWNLXSCJSEQG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14997741

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.930

Distribution Coefficient, logD

2.485

Water Solubility, LogSw

-4.58

Polar Surface Area

52.108

Acid Dissociation Constant (pKa)

11.61

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G327-1651 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G327-1651 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G327-1651?
Check Price and Availability of G327-1651, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G327-1651 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G327-1651
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G327-1651
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G327-1651 available by request