G332-0380 Screening compound: 5-(2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazin-1-yl)-N-(2-morpholinoethyl)-2-thiophenecarboxamide

G332-0380 Screening compound: 5-(2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazin-1-yl)-N-(2-morpholinoethyl)-2-thiophenecarboxamide
G332-0380 Screening compound: 5-(2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazin-1-yl)-N-(2-morpholinoethyl)-2-thiophenecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G332-0380
5-(2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazin-1-yl)-N-(2-morpholinoethyl)-2-thiophenecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G332-0380

Molecular Formula

C18H22N4O2S2 (C18 H22 N4 O2 S2)

Compound Name

5-(2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazin-1-yl)-N-(2-morpholinoethyl)-2-thiophenecarboxamide

IUPAC name

N-[2-(morpholin-4-yl)ethyl]-5-{1H2H3H-pyrido[23-b][14]thiazin-1-yl}thiophene-2-carboxamide

SMILES

O=C(c1ccc(N2c3cccnc3SCC2)s1)NCCN1CCOCC1

InChI

InChI=1S/C18H22N4O2S2/c23-17(19-6-7-21-8-11-24-12-9-21)15-3-4-16(26-15)22-10-13-25-18-14(22)2-1-5-20-18/h1-5H,6-13H2,(H,19,23)

InChI Key

YZTFPJIHMUJFMG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14998622

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.833

Distribution Coefficient, logD

1.804

Water Solubility, LogSw

-2.26

Polar Surface Area

50.924

Acid Dissociation Constant (pKa)

14.07

Base Dissociation Constant (pKb)

6.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.44

G332-0380 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G332-0380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G332-0380?
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What is the minimum amount of G332-0380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G332-0380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G332-0380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G332-0380 available by request