G334-0661 Screening compound: 4-({[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}methyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

G334-0661 Screening compound: 4-({[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}methyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole
G334-0661 Screening compound: 4-({[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}methyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole alternative view

Chemical Structure Depiction of ChemDiv screening compound G334-0661
4-({[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}methyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G334-0661

Molecular Formula

C23H23F3N4O5 (C23 H23 F3 N4 O5)

Compound Name

4-({[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]oxy}methyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

IUPAC name

4-({[13-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[34-b]pyridin-6-yl]oxy}methyl)-5-methyl-2-(345-trimethoxyphenyl)-13-oxazole

SMILES

Cc1nn(C)c2nc(OCc3c(C)oc(-c(cc4OC)cc(OC)c4OC)n3)cc(C(F)(F)F)c12

InChI

InChI=1S/C23H23F3N4O5/c1-11-19-14(23(24,25)26)9-18(28-21(19)30(3)29-11)34-10-15-12(2)35-22(27-15)13-7-16(31-4)20(33-6)17(8-13)32-5/h7-9H,10H2,1-6H3

InChI Key

BHZGLTLSNKWLPY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27135646

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.880

Distribution Coefficient, logD

3.880

Water Solubility, LogSw

-4.30

Polar Surface Area

72.283

Acid Dissociation Constant (pKa)

27.80

Base Dissociation Constant (pKb)

2.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

G334-0661 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G334-0661 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G334-0661?
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What is the minimum amount of G334-0661 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G334-0661
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G334-0661
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G334-0661 available by request