G336-0060 Screening compound: N-cyclopentyl-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazine-1-carboxamide

G336-0060 Screening compound: N-cyclopentyl-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazine-1-carboxamide
G336-0060 Screening compound: N-cyclopentyl-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G336-0060
N-cyclopentyl-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G336-0060

Molecular Formula

C16H21N5OS (C16 H21 N5 OS)

Compound Name

N-cyclopentyl-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazine-1-carboxamide

IUPAC name

N-cyclopentyl-4-{[13]thiazolo[54-b]pyridin-2-yl}piperazine-1-carboxamide

SMILES

O=C(NC1CCCC1)N(CC1)CCN1c1nc2cccnc2s1

InChI

InChI=1S/C16H21N5OS/c22-15(18-12-4-1-2-5-12)20-8-10-21(11-9-20)16-19-13-6-3-7-17-14(13)23-16/h3,6-7,12H,1-2,4-5,8-11H2,(H,18,22)

InChI Key

AFVRSIHXRJGVDQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27135701

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

331.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.920

Distribution Coefficient, logD

2.911

Water Solubility, LogSw

-3.19

Polar Surface Area

49.322

Acid Dissociation Constant (pKa)

17.65

Base Dissociation Constant (pKb)

9.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

56.30

G336-0060 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

GPCR Targeted Library (31838 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G336-0060 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G336-0060?
Check Price and Availability of G336-0060, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G336-0060 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G336-0060
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G336-0060
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G336-0060 available by request