G336-0530 Screening compound: 4-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-4-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)butanamide

G336-0530 Screening compound: 4-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-4-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)butanamide
G336-0530 Screening compound: 4-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-4-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G336-0530
4-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-4-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G336-0530

Molecular Formula

C24H29N5O3S (C24 H29 N5 O3 S)

Compound Name

4-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-4-(4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}piperazin-1-yl)butanamide

IUPAC name

4-oxo-N-{[4-(propan-2-yloxy)phenyl]methyl}-4-(4-{[13]thiazolo[54-b]pyridin-2-yl}piperazin-1-yl)butanamide

SMILES

CC(C)Oc1ccc(CNC(CCC(N(CC2)CCN2c2nc3cccnc3s2)=O)=O)cc1

InChI

InChI=1S/C24H29N5O3S/c1-17(2)32-19-7-5-18(6-8-19)16-26-21(30)9-10-22(31)28-12-14-29(15-13-28)24-27-20-4-3-11-25-23(20)33-24/h3-8,11,17H,9-10,12-16H2,1-2H3,(H,26,30)

InChI Key

ZELHUYPCUNWBIA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27135873

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.565

Distribution Coefficient, logD

2.564

Water Solubility, LogSw

-2.69

Polar Surface Area

69.835

Acid Dissociation Constant (pKa)

13.94

Base Dissociation Constant (pKb)

8.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

G336-0530 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G336-0530 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G336-0530?
Check Price and Availability of G336-0530, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G336-0530 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G336-0530
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G336-0530
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G336-0530 available by request