G346-0278 Screening compound: N-butyl-4-({2,4-dioxo-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxamide

G346-0278 Screening compound: N-butyl-4-({2,4-dioxo-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxamide
G346-0278 Screening compound: N-butyl-4-({2,4-dioxo-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G346-0278
N-butyl-4-({2,4-dioxo-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G346-0278

Molecular Formula

C24H34N4O4S (C24 H34 N4 O4 S)

Compound Name

N-butyl-4-({2,4-dioxo-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H,2H,3H,4H-thieno[3,2-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxamide

IUPAC name

N-butyl-4-({24-dioxo-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H2H3H4H-thieno[32-d]pyrimidin-3-yl}methyl)cyclohexane-1-carboxamide

SMILES

CCCCNC(C1CCC(CN(C(c(scc2)c2N2CC(N3CCCC3)=O)=O)C2=O)CC1)=O

InChI

InChI=1S/C24H34N4O4S/c1-2-3-11-25-22(30)18-8-6-17(7-9-18)15-28-23(31)21-19(10-14-33-21)27(24(28)32)16-20(29)26-12-4-5-13-26/h10,14,17-18H,2-9,11-13,15-16H2,1H3,(H,25,30)

InChI Key

GQHPXJOCBACHHW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14999706

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.62

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.534

Distribution Coefficient, logD

3.534

Water Solubility, LogSw

-3.61

Polar Surface Area

73.762

Acid Dissociation Constant (pKa)

14.41

Base Dissociation Constant (pKb)

0.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.70

G346-0278 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antiviral Annotated Library (21441 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G346-0278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G346-0278?
Check Price and Availability of G346-0278, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G346-0278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G346-0278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G346-0278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G346-0278 available by request