G346-0463 Screening compound: 1-benzyl-3-{[4-(morpholine-4-carbonyl)cyclohexyl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

G346-0463 Screening compound: 1-benzyl-3-{[4-(morpholine-4-carbonyl)cyclohexyl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione
G346-0463 Screening compound: 1-benzyl-3-{[4-(morpholine-4-carbonyl)cyclohexyl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound G346-0463
1-benzyl-3-{[4-(morpholine-4-carbonyl)cyclohexyl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G346-0463

Molecular Formula

C25H29N3O4S (C25 H29 N3 O4 S)

Compound Name

1-benzyl-3-{[4-(morpholine-4-carbonyl)cyclohexyl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

IUPAC name

1-benzyl-3-{[4-(morpholine-4-carbonyl)cyclohexyl]methyl}-1H2H3H4H-thieno[32-d]pyrimidine-24-dione

SMILES

O=C(C1CCC(CN(C(c(scc2)c2N2Cc3ccccc3)=O)C2=O)CC1)N1CCOCC1

InChI

InChI=1S/C25H29N3O4S/c29-23(26-11-13-32-14-12-26)20-8-6-19(7-9-20)17-28-24(30)22-21(10-15-33-22)27(25(28)31)16-18-4-2-1-3-5-18/h1-5,10,15,19-20H,6-9,11-14,16-17H2

InChI Key

SZEQOTJRYDMSNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09249068

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.120

Distribution Coefficient, logD

4.120

Water Solubility, LogSw

-4.23

Polar Surface Area

57.034

Acid Dissociation Constant (pKa)

23.65

Base Dissociation Constant (pKb)

-1.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

48.00

G346-0463 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G346-0463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G346-0463?
Check Price and Availability of G346-0463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G346-0463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G346-0463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G346-0463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G346-0463 available by request