G353-0349 Screening compound: 2-[4-(4-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-phenylacetamide

G353-0349 Screening compound: 2-[4-(4-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-phenylacetamide
G353-0349 Screening compound: 2-[4-(4-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-phenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G353-0349
2-[4-(4-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-phenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G353-0349

Molecular Formula

C23H18ClN3O2 (C23 H18 ClN3 O2)

Compound Name

2-[4-(4-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,5-benzodiazepin-1-yl]-N-phenylacetamide

IUPAC name

2-[4-(4-chlorophenyl)-2-oxo-23-dihydro-1H-15-benzodiazepin-1-yl]-N-phenylacetamide

SMILES

O=C(CN(c(cccc1)c1N=C(C1)c(cc2)ccc2Cl)C1=O)Nc1ccccc1

InChI

InChI=1S/C23H18ClN3O2/c24-17-12-10-16(11-13-17)20-14-23(29)27(21-9-5-4-8-19(21)26-20)15-22(28)25-18-6-2-1-3-7-18/h1-13H,14-15H2,(H,25,28)

InChI Key

CAFPPBAAARELCW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15000888

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.87

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.454

Distribution Coefficient, logD

4.454

Water Solubility, LogSw

-4.79

Polar Surface Area

47.739

Acid Dissociation Constant (pKa)

12.51

Base Dissociation Constant (pKb)

0.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

G353-0349 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G353-0349 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G353-0349?
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What is the minimum amount of G353-0349 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G353-0349
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G353-0349
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G353-0349 available by request