G354-1778 Screening compound: 3-(2-methylphenyl)-N-(5-methylpyridin-2-yl)-3-(1H-pyrrol-1-yl)propanamide

G354-1778 Screening compound: 3-(2-methylphenyl)-N-(5-methylpyridin-2-yl)-3-(1H-pyrrol-1-yl)propanamide
G354-1778 Screening compound: 3-(2-methylphenyl)-N-(5-methylpyridin-2-yl)-3-(1H-pyrrol-1-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G354-1778
3-(2-methylphenyl)-N-(5-methylpyridin-2-yl)-3-(1H-pyrrol-1-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G354-1778

Molecular Formula

C20H21N3O (C20 H21 N3 O)

Compound Name

3-(2-methylphenyl)-N-(5-methylpyridin-2-yl)-3-(1H-pyrrol-1-yl)propanamide

IUPAC name

3-(2-methylphenyl)-N-(5-methylpyridin-2-yl)-3-(1H-pyrrol-1-yl)propanamide

SMILES

Cc(cc1)cnc1NC(CC(c1c(C)cccc1)n1cccc1)=O

InChI

InChI=1S/C20H21N3O/c1-15-9-10-19(21-14-15)22-20(24)13-18(23-11-5-6-12-23)17-8-4-3-7-16(17)2/h3-12,14,18H,13H2,1-2H3,(H,21,22,24)/t18-/m0/s1

InChI Key

RIGCWIMJXUWJAG-SFHVURJKSA-N

MDL Number (MFCD)

MFCD15001388

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

319.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.444

Distribution Coefficient, logD

4.441

Water Solubility, LogSw

-4.11

Polar Surface Area

36.343

Acid Dissociation Constant (pKa)

9.55

Base Dissociation Constant (pKb)

4.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

G354-1778 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G354-1778 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G354-1778?
Check Price and Availability of G354-1778, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G354-1778 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G354-1778
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G354-1778
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G354-1778 available by request