G357-1673 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-butanamidobenzoate

G357-1673 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-butanamidobenzoate
G357-1673 Screening compound: {5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-butanamidobenzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-1673
{5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-butanamidobenzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-1673

Molecular Formula

C18H17N3O4S (C18 H17 N3 O4 S)

Compound Name

{5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-butanamidobenzoate

IUPAC name

{5-oxo-5H-[13]thiazolo[32-a]pyrimidin-7-yl}methyl 2-butanamidobenzoate

SMILES

CCCC(Nc(cccc1)c1C(OCC(N=C1SC=CN11)=CC1=O)=O)=O

InChI

InChI=1S/C18H17N3O4S/c1-2-5-15(22)20-14-7-4-3-6-13(14)17(24)25-11-12-10-16(23)21-8-9-26-18(21)19-12/h3-4,6-10H,2,5,11H2,1H3,(H,20,22)

InChI Key

QBFRBSMCAHOIFT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15002299

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.42

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.686

Distribution Coefficient, logD

1.672

Water Solubility, LogSw

-2.67

Polar Surface Area

69.503

Acid Dissociation Constant (pKa)

8.87

Base Dissociation Constant (pKb)

-2.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G357-1673 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G357-1673 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-1673?
Check Price and Availability of G357-1673, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G357-1673 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-1673
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-1673
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-1673 available by request