G357-1912 Screening compound: {3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(4-fluorobenzamido)benzoate

G357-1912 Screening compound: {3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(4-fluorobenzamido)benzoate
G357-1912 Screening compound: {3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(4-fluorobenzamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-1912
{3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(4-fluorobenzamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-1912

Molecular Formula

C22H16FN3O4S (C22 H16 FN3 O4 S)

Compound Name

{3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-(4-fluorobenzamido)benzoate

IUPAC name

{3-methyl-5-oxo-5H-[13]thiazolo[32-a]pyrimidin-7-yl}methyl 2-(4-fluorobenzamido)benzoate

SMILES

CC(N12)=CSC2=NC(COC(c(cccc2)c2NC(c(cc2)ccc2F)=O)=O)=CC1=O

InChI

InChI=1S/C22H16FN3O4S/c1-13-12-31-22-24-16(10-19(27)26(13)22)11-30-21(29)17-4-2-3-5-18(17)25-20(28)14-6-8-15(23)9-7-14/h2-10,12H,11H2,1H3,(H,25,28)

InChI Key

CHMJWYRTDCYWGB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15002388

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.45

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.198

Distribution Coefficient, logD

2.353

Water Solubility, LogSw

-3.65

Polar Surface Area

69.109

Acid Dissociation Constant (pKa)

6.62

Base Dissociation Constant (pKb)

0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

G357-1912 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anticancer Library (62698 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G357-1912 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-1912?
Check Price and Availability of G357-1912, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G357-1912 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-1912
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-1912
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-1912 available by request