G357-2170 Screening compound: {2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-propanamidobenzoate

G357-2170 Screening compound: {2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-propanamidobenzoate
G357-2170 Screening compound: {2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-propanamidobenzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-2170
{2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-propanamidobenzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-2170

Molecular Formula

C18H17N3O4S (C18 H17 N3 O4 S)

Compound Name

{2-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-7-yl}methyl 2-propanamidobenzoate

IUPAC name

{2-methyl-5-oxo-5H-[13]thiazolo[32-a]pyrimidin-7-yl}methyl 2-propanamidobenzoate

SMILES

CCC(Nc(cccc1)c1C(OCC(N=C1SC(C)=CN11)=CC1=O)=O)=O

InChI

InChI=1S/C18H17N3O4S/c1-3-15(22)20-14-7-5-4-6-13(14)17(24)25-10-12-8-16(23)21-9-11(2)26-18(21)19-12/h4-9H,3,10H2,1-2H3,(H,20,22)

InChI Key

OYDFRTJBKSUNFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15002475

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.42

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.759

Distribution Coefficient, logD

1.750

Water Solubility, LogSw

-2.75

Polar Surface Area

70.022

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

1.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G357-2170 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G357-2170 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-2170?
Check Price and Availability of G357-2170, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G357-2170 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-2170
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-2170
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-2170 available by request