G357-4936 Screening compound: {2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(4-butylcyclohexaneamido)-4-chlorobenzoate

G357-4936 Screening compound: {2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(4-butylcyclohexaneamido)-4-chlorobenzoate
G357-4936 Screening compound: {2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(4-butylcyclohexaneamido)-4-chlorobenzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G357-4936
{2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(4-butylcyclohexaneamido)-4-chlorobenzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G357-4936

Molecular Formula

C26H30ClN3O5 (C26 H30 ClN3 O5)

Compound Name

{2-methyl-7-oxo-7H-[1,2]oxazolo[2,3-a]pyrimidin-5-yl}methyl 3-(4-butylcyclohexaneamido)-4-chlorobenzoate

IUPAC name

{2-methyl-7-oxo-7H-[12]oxazolo[23-a]pyrimidin-5-yl}methyl 3-(4-butylcyclohexaneamido)-4-chlorobenzoate

SMILES

CCCCC(CC1)CCC1C(Nc(cc(cc1)C(OCC(N=C2N3OC(C)=C2)=CC3=O)=O)c1Cl)=O

InChI

InChI=1S/C26H30ClN3O5/c1-3-4-5-17-6-8-18(9-7-17)25(32)29-22-13-19(10-11-21(22)27)26(33)34-15-20-14-24(31)30-23(28-20)12-16(2)35-30/h10-14,17-18H,3-9,15H2,1-2H3,(H,29,32)

InChI Key

CYFNOWMKWCIZEA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137401

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.99

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.269

Distribution Coefficient, logD

5.266

Water Solubility, LogSw

-5.89

Polar Surface Area

82.145

Acid Dissociation Constant (pKa)

9.62

Base Dissociation Constant (pKb)

3.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

G357-4936 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GABA Library (7115 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G357-4936 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G357-4936?
Check Price and Availability of G357-4936, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G357-4936 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G357-4936
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G357-4936
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G357-4936 available by request