G364-1252 Screening compound: methyl 4-({2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetyl}amino)benzoate

G364-1252 Screening compound: methyl 4-({2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetyl}amino)benzoate
G364-1252 Screening compound: methyl 4-({2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetyl}amino)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G364-1252
methyl 4-({2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetyl}amino)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G364-1252

Molecular Formula

C19H20FN3O5S (C19 H20 FN3 O5 S)

Compound Name

methyl 4-({2-[5-(2-fluorobenzyl)-1,1-dioxo-1lambda~6~,2,5-thiadiazolan-2-yl]acetyl}amino)benzoate

IUPAC name

methyl 4-(2-{5-[(2-fluorophenyl)methyl]-11-dioxo-1lambda625-thiadiazolidin-2-yl}acetamido)benzoate

SMILES

COC(c(cc1)ccc1NC(CN(CCN1Cc(cccc2)c2F)S1(=O)=O)=O)=O

InChI

InChI=1S/C19H20FN3O5S/c1-28-19(25)14-6-8-16(9-7-14)21-18(24)13-23-11-10-22(29(23,26)27)12-15-4-2-3-5-17(15)20/h2-9H,10-13H2,1H3,(H,21,24)

InChI Key

DRRUDTDGPSMBMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27137442

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.45

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.610

Distribution Coefficient, logD

2.610

Water Solubility, LogSw

-3.07

Polar Surface Area

81.068

Acid Dissociation Constant (pKa)

11.09

Base Dissociation Constant (pKb)

-1.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

G364-1252 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G364-1252 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G364-1252?
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What is the minimum amount of G364-1252 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G364-1252
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G364-1252
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G364-1252 available by request