G365-0057 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-cyclohexylpiperazine

G365-0057 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-cyclohexylpiperazine
G365-0057 Screening compound: 1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-cyclohexylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G365-0057
1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-cyclohexylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G365-0057

Molecular Formula

C22H28N4O (C22 H28 N4 O)

Compound Name

1-{1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-cyclohexylpiperazine

IUPAC name

1-{1H4H5H-benzo[g]indazole-3-carbonyl}-4-cyclohexylpiperazine

SMILES

O=C(c1n[nH]c-2c1CCc1c2cccc1)N(CC1)CCN1C1CCCCC1

InChI

InChI=1S/C22H28N4O/c27-22(26-14-12-25(13-15-26)17-7-2-1-3-8-17)21-19-11-10-16-6-4-5-9-18(16)20(19)23-24-21/h4-6,9,17H,1-3,7-8,10-15H2,(H,23,24)

InChI Key

BKPRAOXHWHDLMU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003718

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.747

Distribution Coefficient, logD

3.583

Water Solubility, LogSw

-4.05

Polar Surface Area

44.022

Acid Dissociation Constant (pKa)

6.35

Base Dissociation Constant (pKb)

7.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.50

G365-0057 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

GPCR Targeted Library (31838 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Immune system
Targets:
  • GPCR
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G365-0057 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G365-0057?
Check Price and Availability of G365-0057, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G365-0057 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G365-0057
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G365-0057
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G365-0057 available by request