G365-0176 Screening compound: N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-1H,4H,5H-benzo[g]indazole-3-carboxamide

G365-0176 Screening compound: N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-1H,4H,5H-benzo[g]indazole-3-carboxamide
G365-0176 Screening compound: N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-1H,4H,5H-benzo[g]indazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G365-0176
N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-1H,4H,5H-benzo[g]indazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G365-0176

Molecular Formula

C27H33N5O (C27 H33 N5 O)

Compound Name

N-{3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propyl}-1H,4H,5H-benzo[g]indazole-3-carboxamide

IUPAC name

N-{3-[4-(25-dimethylphenyl)piperazin-1-yl]propyl}-1H4H5H-benzo[g]indazole-3-carboxamide

SMILES

Cc1cc(N2CCN(CCCNC(c3n[nH]c-4c3CCc3c4cccc3)=O)CC2)c(C)cc1

InChI

InChI=1S/C27H33N5O/c1-19-8-9-20(2)24(18-19)32-16-14-31(15-17-32)13-5-12-28-27(33)26-23-11-10-21-6-3-4-7-22(21)25(23)29-30-26/h3-4,6-9,18H,5,10-17H2,1-2H3,(H,28,33)(H,29,30)

InChI Key

CRFHEUVTMUCXNK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003787

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.59

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.614

Distribution Coefficient, logD

3.468

Water Solubility, LogSw

-4.29

Polar Surface Area

55.477

Acid Dissociation Constant (pKa)

6.17

Base Dissociation Constant (pKb)

8.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.70

G365-0176 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G365-0176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G365-0176?
Check Price and Availability of G365-0176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G365-0176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G365-0176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G365-0176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G365-0176 available by request