G365-0264 Screening compound: 1-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-methylpiperazine

G365-0264 Screening compound: 1-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-methylpiperazine
G365-0264 Screening compound: 1-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-methylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G365-0264
1-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-methylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G365-0264

Molecular Formula

C18H22N4O2 (C18 H22 N4 O2)

Compound Name

1-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}-4-methylpiperazine

IUPAC name

1-{7-methoxy-1H4H5H-benzo[g]indazole-3-carbonyl}-4-methylpiperazine

SMILES

CN(CC1)CCN1C(c1n[nH]c-2c1CCc1c2ccc(OC)c1)=O

InChI

InChI=1S/C18H22N4O2/c1-21-7-9-22(10-8-21)18(23)17-15-5-3-12-11-13(24-2)4-6-14(12)16(15)19-20-17/h4,6,11H,3,5,7-10H2,1-2H3,(H,19,20)

InChI Key

FOFISFIVHMRWGX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15003852

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

326.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.011

Distribution Coefficient, logD

1.879

Water Solubility, LogSw

-2.83

Polar Surface Area

51.949

Acid Dissociation Constant (pKa)

6.65

Base Dissociation Constant (pKb)

6.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

G365-0264 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G365-0264 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G365-0264?
Check Price and Availability of G365-0264, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G365-0264 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G365-0264
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G365-0264
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G365-0264 available by request