G366-1170 Screening compound: 1-benzoyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-2,3-dihydro-1H-indole-2-carboxamide

G366-1170 Screening compound: 1-benzoyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-2,3-dihydro-1H-indole-2-carboxamide
G366-1170 Screening compound: 1-benzoyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-2,3-dihydro-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G366-1170
1-benzoyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-2,3-dihydro-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G366-1170

Molecular Formula

C29H31FN4O2 (C29 H31 FN4 O2)

Compound Name

1-benzoyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-2,3-dihydro-1H-indole-2-carboxamide

IUPAC name

1-benzoyl-N-{3-[4-(4-fluorophenyl)piperazin-1-yl]propyl}-23-dihydro-1H-indole-2-carboxamide

SMILES

O=C(C(C1)N(C(c2ccccc2)=O)c2c1cccc2)NCCCN(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C29H31FN4O2/c30-24-11-13-25(14-12-24)33-19-17-32(18-20-33)16-6-15-31-28(35)27-21-23-9-4-5-10-26(23)34(27)29(36)22-7-2-1-3-8-22/h1-5,7-14,27H,6,15-21H2,(H,31,35)/t27-/m0/s1

InChI Key

VGPMDPDTSBKPRR-MHZLTWQESA-N

MDL Number (MFCD)

MFCD15004509

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.714

Distribution Coefficient, logD

3.128

Water Solubility, LogSw

-4.03

Polar Surface Area

46.763

Acid Dissociation Constant (pKa)

14.88

Base Dissociation Constant (pKb)

7.86

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.00

G366-1170 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with G366-1170 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G366-1170?
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What is the minimum amount of G366-1170 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G366-1170
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G366-1170
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G366-1170 available by request