G373-2018 Screening compound: 3-{2-[5-(dimethylsulfamoyl)-1H-1,2,3-benzotriazol-1-yl]ethyl}-1-(3,4,5-trimethoxyphenyl)urea

G373-2018 Screening compound: 3-{2-[5-(dimethylsulfamoyl)-1H-1,2,3-benzotriazol-1-yl]ethyl}-1-(3,4,5-trimethoxyphenyl)urea
G373-2018 Screening compound: 3-{2-[5-(dimethylsulfamoyl)-1H-1,2,3-benzotriazol-1-yl]ethyl}-1-(3,4,5-trimethoxyphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-2018
3-{2-[5-(dimethylsulfamoyl)-1H-1,2,3-benzotriazol-1-yl]ethyl}-1-(3,4,5-trimethoxyphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-2018

Molecular Formula

C20H26N6O6S (C20 H26 N6 O6 S)

Compound Name

3-{2-[5-(dimethylsulfamoyl)-1H-1,2,3-benzotriazol-1-yl]ethyl}-1-(3,4,5-trimethoxyphenyl)urea

IUPAC name

3-{2-[5-(dimethylsulfamoyl)-1H-123-benzotriazol-1-yl]ethyl}-1-(345-trimethoxyphenyl)urea

SMILES

CN(C)S(c(cc1)cc2c1n(CCNC(Nc(cc1OC)cc(OC)c1OC)=O)nn2)(=O)=O

InChI

InChI=1S/C20H26N6O6S/c1-25(2)33(28,29)14-6-7-16-15(12-14)23-24-26(16)9-8-21-20(27)22-13-10-17(30-3)19(32-5)18(11-13)31-4/h6-7,10-12H,8-9H2,1-5H3,(H2,21,22,27)

InChI Key

SMUOFOPEOBLDDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15006060

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.53

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

12

Partition Coefficient, logP

1.081

Distribution Coefficient, logD

1.081

Water Solubility, LogSw

-2.49

Polar Surface Area

116.023

Acid Dissociation Constant (pKa)

11.35

Base Dissociation Constant (pKb)

2.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

G373-2018 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

KRAS-Targeted Library (16000 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G373-2018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-2018?
Check Price and Availability of G373-2018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-2018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-2018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-2018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-2018 available by request