G373-2121 Screening compound: N-(4-chlorophenyl)-4-{4-[(4-fluorophenyl)methyl]-2,3-dioxopiperazin-1-yl}butanamide

G373-2121 Screening compound: N-(4-chlorophenyl)-4-{4-[(4-fluorophenyl)methyl]-2,3-dioxopiperazin-1-yl}butanamide
G373-2121 Screening compound: N-(4-chlorophenyl)-4-{4-[(4-fluorophenyl)methyl]-2,3-dioxopiperazin-1-yl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-2121
N-(4-chlorophenyl)-4-{4-[(4-fluorophenyl)methyl]-2,3-dioxopiperazin-1-yl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-2121

Molecular Formula

C21H21ClFN3O3 (C21 H21 ClFN3 O3)

Compound Name

N-(4-chlorophenyl)-4-{4-[(4-fluorophenyl)methyl]-2,3-dioxopiperazin-1-yl}butanamide

IUPAC name

N-(4-chlorophenyl)-4-{4-[(4-fluorophenyl)methyl]-23-dioxopiperazin-1-yl}butanamide

SMILES

O=C(CCCN(CCN(Cc(cc1)ccc1F)C1=O)C1=O)Nc(cc1)ccc1Cl

InChI

InChI=1S/C21H21ClFN3O3/c22-16-5-9-18(10-6-16)24-19(27)2-1-11-25-12-13-26(21(29)20(25)28)14-15-3-7-17(23)8-4-15/h3-10H,1-2,11-14H2,(H,24,27)

InChI Key

NCBBVWDRTAHMDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15006097

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.87

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.183

Distribution Coefficient, logD

2.182

Water Solubility, LogSw

-3.11

Polar Surface Area

56.411

Acid Dissociation Constant (pKa)

10.73

Base Dissociation Constant (pKb)

3.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

G373-2121 in Drug Discovery

Included in Screening Libraries

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G373-2121 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-2121?
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What is the minimum amount of G373-2121 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-2121
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-2121
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-2121 available by request