G373-3708 Screening compound: 1-(3-methoxybenzenesulfonyl)-4-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

G373-3708 Screening compound: 1-(3-methoxybenzenesulfonyl)-4-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine
G373-3708 Screening compound: 1-(3-methoxybenzenesulfonyl)-4-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3708
1-(3-methoxybenzenesulfonyl)-4-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3708

Molecular Formula

C25H27N5O4S (C25 H27 N5 O4 S)

Compound Name

1-(3-methoxybenzenesulfonyl)-4-{[3-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}piperazine

IUPAC name

1-(3-methoxybenzenesulfonyl)-4-{[3-(4-methoxyphenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}piperazine

SMILES

COc(cc1)ccc1-n1c(nccc2)c2nc1CN(CC1)CCN1S(c1cc(OC)ccc1)(=O)=O

InChI

InChI=1S/C25H27N5O4S/c1-33-20-10-8-19(9-11-20)30-24(27-23-7-4-12-26-25(23)30)18-28-13-15-29(16-14-28)35(31,32)22-6-3-5-21(17-22)34-2/h3-12,17H,13-16,18H2,1-2H3

InChI Key

ZIRIJPWBRFQEQS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27138087

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.899

Distribution Coefficient, logD

2.898

Water Solubility, LogSw

-3.37

Polar Surface Area

72.132

Acid Dissociation Constant (pKa)

28.13

Base Dissociation Constant (pKb)

4.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

G373-3708 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G373-3708 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3708?
Check Price and Availability of G373-3708, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G373-3708 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3708
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3708
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3708 available by request