G373-3814 Screening compound: 4-{[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(naphthalen-2-yl)piperazine-1-carboxamide

G373-3814 Screening compound: 4-{[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(naphthalen-2-yl)piperazine-1-carboxamide
G373-3814 Screening compound: 4-{[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(naphthalen-2-yl)piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G373-3814
4-{[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(naphthalen-2-yl)piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G373-3814

Molecular Formula

C29H28N6O (C29 H28 N6 O)

Compound Name

4-{[3-(3-methylphenyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}-N-(naphthalen-2-yl)piperazine-1-carboxamide

IUPAC name

4-{[3-(3-methylphenyl)-3H-imidazo[45-b]pyridin-2-yl]methyl}-N-(naphthalen-2-yl)piperazine-1-carboxamide

SMILES

Cc1cccc(-n2c(nccc3)c3nc2CN(CC2)CCN2C(Nc2cc3ccccc3cc2)=O)c1

InChI

InChI=1S/C29H28N6O/c1-21-6-4-9-25(18-21)35-27(32-26-10-5-13-30-28(26)35)20-33-14-16-34(17-15-33)29(36)31-24-12-11-22-7-2-3-8-23(22)19-24/h2-13,18-19H,14-17,20H2,1H3,(H,31,36)

InChI Key

OMMJOFFIISFSPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27138127

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.58

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.709

Distribution Coefficient, logD

4.688

Water Solubility, LogSw

-4.79

Polar Surface Area

50.531

Acid Dissociation Constant (pKa)

13.83

Base Dissociation Constant (pKb)

6.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.70

G373-3814 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G373-3814 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G373-3814?
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What is the minimum amount of G373-3814 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G373-3814
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G373-3814
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G373-3814 available by request