G378-0016 Screening compound: N-(4-chlorobenzyl)[3-(1H-imidazol-1-ylmethyl)-4-methoxyphenyl]methanamine

G378-0016 Screening compound: N-(4-chlorobenzyl)[3-(1H-imidazol-1-ylmethyl)-4-methoxyphenyl]methanamine
G378-0016 Screening compound: N-(4-chlorobenzyl)[3-(1H-imidazol-1-ylmethyl)-4-methoxyphenyl]methanamine alternative view

Chemical Structure Depiction of ChemDiv screening compound G378-0016
N-(4-chlorobenzyl)[3-(1H-imidazol-1-ylmethyl)-4-methoxyphenyl]methanamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G378-0016

Molecular Formula

C19H20ClN3O (C19 H20 ClN3 O)

Compound Name

N-(4-chlorobenzyl)[3-(1H-imidazol-1-ylmethyl)-4-methoxyphenyl]methanamine

IUPAC name

[(4-chlorophenyl)methyl]({3-[(1H-imidazol-1-yl)methyl]-4-methoxyphenyl}methyl)amine

SMILES

COc1c(Cn2cncc2)cc(CNCc(cc2)ccc2Cl)cc1

InChI

InChI=1S/C19H20ClN3O/c1-24-19-7-4-16(10-17(19)13-23-9-8-21-14-23)12-22-11-15-2-5-18(20)6-3-15/h2-10,14,22H,11-13H2,1H3

InChI Key

BJAYBZCRQREEPE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15006630

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.84

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.110

Distribution Coefficient, logD

2.271

Water Solubility, LogSw

-3.53

Polar Surface Area

32.185

Acid Dissociation Constant (pKa)

23.68

Base Dissociation Constant (pKb)

8.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.05

G378-0016 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G378-0016 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G378-0016?
Check Price and Availability of G378-0016, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G378-0016 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G378-0016
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G378-0016
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G378-0016 available by request