G394-0063 Screening compound: ethyl 4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine-1-carboxylate

G394-0063 Screening compound: ethyl 4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine-1-carboxylate
G394-0063 Screening compound: ethyl 4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound G394-0063
ethyl 4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G394-0063

Molecular Formula

C20H28N6O3S (C20 H28 N6 O3 S)

Compound Name

ethyl 4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine-1-carboxylate

IUPAC name

ethyl 4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[23-d]pyrimidine-6-carbonyl]piperazine-1-carboxylate

SMILES

CCOC(N(CC1)CCN1C(c1c(C)c2c(N3CCN(C)CC3)ncnc2s1)=O)=O

InChI

InChI=1S/C20H28N6O3S/c1-4-29-20(28)26-11-9-25(10-12-26)19(27)16-14(2)15-17(21-13-22-18(15)30-16)24-7-5-23(3)6-8-24/h13H,4-12H2,1-3H3

InChI Key

RGWMAVXVAUJWMH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15007225

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.55

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.313

Distribution Coefficient, logD

1.848

Water Solubility, LogSw

-2.15

Polar Surface Area

67.444

Acid Dissociation Constant (pKa)

22.05

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

G394-0063 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G394-0063 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G394-0063?
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What is the minimum amount of G394-0063 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G394-0063
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G394-0063
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G394-0063 available by request