G394-0146 Screening compound: 1-(5-chloro-2-methylphenyl)-4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine

G394-0146 Screening compound: 1-(5-chloro-2-methylphenyl)-4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine
G394-0146 Screening compound: 1-(5-chloro-2-methylphenyl)-4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G394-0146
1-(5-chloro-2-methylphenyl)-4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G394-0146

Molecular Formula

C24H29ClN6OS (C24 H29 ClN6 OS)

Compound Name

1-(5-chloro-2-methylphenyl)-4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carbonyl]piperazine

IUPAC name

1-(5-chloro-2-methylphenyl)-4-[5-methyl-4-(4-methylpiperazin-1-yl)thieno[23-d]pyrimidine-6-carbonyl]piperazine

SMILES

Cc1c(C(N(CC2)CCN2c2c(C)ccc(Cl)c2)=O)sc2c1c(N1CCN(C)CC1)ncn2

InChI

InChI=1S/C24H29ClN6OS/c1-16-4-5-18(25)14-19(16)29-10-12-31(13-11-29)24(32)21-17(2)20-22(26-15-27-23(20)33-21)30-8-6-28(3)7-9-30/h4-5,14-15H,6-13H2,1-3H3

InChI Key

FFZFMZORTYRLOF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15007262

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.05

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.693

Distribution Coefficient, logD

4.228

Water Solubility, LogSw

-4.84

Polar Surface Area

47.623

Acid Dissociation Constant (pKa)

22.05

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.80

G394-0146 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Infections
  • Immune system
  • animal
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G394-0146 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G394-0146?
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What is the minimum amount of G394-0146 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G394-0146
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G394-0146
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G394-0146 available by request