G394-1619 Screening compound: N-[2-(5-CHLORO-1H-INDOL-3-YL)ETHYL]-4-(4-ETHYLPIPERAZIN-1-YL)-5-METHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE

G394-1619 Screening compound: N-[2-(5-CHLORO-1H-INDOL-3-YL)ETHYL]-4-(4-ETHYLPIPERAZIN-1-YL)-5-METHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE
G394-1619 Screening compound: N-[2-(5-CHLORO-1H-INDOL-3-YL)ETHYL]-4-(4-ETHYLPIPERAZIN-1-YL)-5-METHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound G394-1619
N-[2-(5-CHLORO-1H-INDOL-3-YL)ETHYL]-4-(4-ETHYLPIPERAZIN-1-YL)-5-METHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G394-1619

Molecular Formula

C24H27ClN6OS (C24 H27 ClN6 OS)

Compound Name

N-[2-(5-CHLORO-1H-INDOL-3-YL)ETHYL]-4-(4-ETHYLPIPERAZIN-1-YL)-5-METHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE

IUPAC name

n/a

SMILES

CCN(CC1)CCN1c1ncnc2c1c(C)c(C(NCCc1c[nH]c(cc3)c1cc3Cl)=O)s2

InChI

InChI=1S/C24H27ClN6OS/c1-3-30-8-10-31(11-9-30)22-20-15(2)21(33-24(20)29-14-28-22)23(32)26-7-6-16-13-27-19-5-4-17(25)12-18(16)19/h4-5,12-14,27H,3,6-11H2,1-2H3,(H,26,32)

InChI Key

RGZCWEDMXMGVRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27138556

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.04

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.488

Distribution Coefficient, logD

3.917

Water Solubility, LogSw

-4.59

Polar Surface Area

62.201

Acid Dissociation Constant (pKa)

12.46

Base Dissociation Constant (pKb)

7.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

G394-1619 in Drug Discovery

Included in Screening Libraries

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Receptor's ligands
Targets:
  • GPCR
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G394-1619 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G394-1619?
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What is the minimum amount of G394-1619 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G394-1619
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G394-1619
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G394-1619 available by request