G395-1648 Screening compound: N-cyclohexyl-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

G395-1648 Screening compound: N-cyclohexyl-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide
G395-1648 Screening compound: N-cyclohexyl-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G395-1648
N-cyclohexyl-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G395-1648

Molecular Formula

C21H31N7O2 (C21 H31 N7 O2)

Compound Name

N-cyclohexyl-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

IUPAC name

N-cyclohexyl-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[124]triazolo[43-b]pyridazin-3-yl)propanamide

SMILES

O=C(CCc1nnc(cc2)n1nc2NCCCN(CCC1)C1=O)NC1CCCCC1

InChI

InChI=1S/C21H31N7O2/c29-20(23-16-6-2-1-3-7-16)12-11-19-25-24-18-10-9-17(26-28(18)19)22-13-5-15-27-14-4-8-21(27)30/h9-10,16H,1-8,11-15H2,(H,22,26)(H,23,29)

InChI Key

AWEKTNDTBNPVRV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15008173

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.613

Distribution Coefficient, logD

0.613

Water Solubility, LogSw

-1.69

Polar Surface Area

85.725

Acid Dissociation Constant (pKa)

15.48

Base Dissociation Constant (pKb)

1.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

66.70

G395-1648 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Autophagy-Targeted Library (4564 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G395-1648 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G395-1648?
Check Price and Availability of G395-1648, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G395-1648 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G395-1648
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G395-1648
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G395-1648 available by request