G395-1710 Screening compound: N-{2-[4-(methylsulfanyl)phenyl]ethyl}-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

G395-1710 Screening compound: N-{2-[4-(methylsulfanyl)phenyl]ethyl}-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide
G395-1710 Screening compound: N-{2-[4-(methylsulfanyl)phenyl]ethyl}-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G395-1710
N-{2-[4-(methylsulfanyl)phenyl]ethyl}-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G395-1710

Molecular Formula

C24H31N7O2S (C24 H31 N7 O2 S)

Compound Name

N-{2-[4-(methylsulfanyl)phenyl]ethyl}-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)propanamide

IUPAC name

N-{2-[4-(methylsulfanyl)phenyl]ethyl}-3-(6-{[3-(2-oxopyrrolidin-1-yl)propyl]amino}-[124]triazolo[43-b]pyridazin-3-yl)propanamide

SMILES

CSc1ccc(CCNC(CCc2nnc(cc3)n2nc3NCCCN(CCC2)C2=O)=O)cc1

InChI

InChI=1S/C24H31N7O2S/c1-34-19-7-5-18(6-8-19)13-15-26-23(32)12-11-22-28-27-21-10-9-20(29-31(21)22)25-14-3-17-30-16-2-4-24(30)33/h5-10H,2-4,11-17H2,1H3,(H,25,29)(H,26,32)

InChI Key

HYKJBRNHVOPKAF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15008210

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.62

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

13.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.763

Distribution Coefficient, logD

0.763

Water Solubility, LogSw

-2.20

Polar Surface Area

85.842

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

1.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.83

G395-1710 in Drug Discovery

Included in Screening Libraries

Dark Chemical Matter Library (18430 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with G395-1710 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G395-1710?
Check Price and Availability of G395-1710, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G395-1710 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G395-1710
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G395-1710
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G395-1710 available by request