G397-1219 Screening compound: 2-{methyl[5-(2-oxopiperidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}-N-[(thiophen-2-yl)methyl]acetamide

G397-1219 Screening compound: 2-{methyl[5-(2-oxopiperidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}-N-[(thiophen-2-yl)methyl]acetamide
G397-1219 Screening compound: 2-{methyl[5-(2-oxopiperidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}-N-[(thiophen-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G397-1219
2-{methyl[5-(2-oxopiperidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}-N-[(thiophen-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G397-1219

Molecular Formula

C15H19N5O2S2 (C15 H19 N5 O2 S2)

Compound Name

2-{methyl[5-(2-oxopiperidin-1-yl)-1,3,4-thiadiazol-2-yl]amino}-N-[(thiophen-2-yl)methyl]acetamide

IUPAC name

2-{methyl[5-(2-oxopiperidin-1-yl)-134-thiadiazol-2-yl]amino}-N-[(thiophen-2-yl)methyl]acetamide

SMILES

CN(CC(NCc1cccs1)=O)c1nnc(N(CCCC2)C2=O)s1

InChI

InChI=1S/C15H19N5O2S2/c1-19(10-12(21)16-9-11-5-4-8-23-11)14-17-18-15(24-14)20-7-3-2-6-13(20)22/h4-5,8H,2-3,6-7,9-10H2,1H3,(H,16,21)

InChI Key

RRQIWMFYTXSMNF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15008996

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.763

Distribution Coefficient, logD

1.763

Water Solubility, LogSw

-2.48

Polar Surface Area

68.267

Acid Dissociation Constant (pKa)

13.89

Base Dissociation Constant (pKb)

3.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.70

G397-1219 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G397-1219 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G397-1219?
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What is the minimum amount of G397-1219 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G397-1219
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G397-1219
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G397-1219 available by request