G404-0866 Screening compound: N-(2,5-dimethylphenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]piperidine-3-carboxamide

G404-0866 Screening compound: N-(2,5-dimethylphenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]piperidine-3-carboxamide
G404-0866 Screening compound: N-(2,5-dimethylphenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G404-0866
N-(2,5-dimethylphenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G404-0866

Molecular Formula

C18H24N4O3S (C18 H24 N4 O3 S)

Compound Name

N-(2,5-dimethylphenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-(25-dimethylphenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]piperidine-3-carboxamide

SMILES

Cc1cc(NC(C(CCC2)CN2S(c2cn(C)cn2)(=O)=O)=O)c(C)cc1

InChI

InChI=1S/C18H24N4O3S/c1-13-6-7-14(2)16(9-13)20-18(23)15-5-4-8-22(10-15)26(24,25)17-11-21(3)12-19-17/h6-7,9,11-12,15H,4-5,8,10H2,1-3H3,(H,20,23)/t15-/m0/s1

InChI Key

KMCCMDKBNHTRCM-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD15009671

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

376.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.118

Distribution Coefficient, logD

1.118

Water Solubility, LogSw

-2.34

Polar Surface Area

66.687

Acid Dissociation Constant (pKa)

11.40

Base Dissociation Constant (pKb)

-0.17

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.40

G404-0866 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Human Proteases Annotated Library (2868 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G404-0866 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G404-0866?
Check Price and Availability of G404-0866, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G404-0866 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G404-0866
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G404-0866
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G404-0866 available by request