G404-2445 Screening compound: 1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]-N-(4-methylpyridin-2-yl)piperidine-3-carboxamide

G404-2445 Screening compound: 1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]-N-(4-methylpyridin-2-yl)piperidine-3-carboxamide
G404-2445 Screening compound: 1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]-N-(4-methylpyridin-2-yl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G404-2445
1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]-N-(4-methylpyridin-2-yl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G404-2445

Molecular Formula

C17H23N5O3S (C17 H23 N5 O3 S)

Compound Name

1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]-N-(4-methylpyridin-2-yl)piperidine-3-carboxamide

IUPAC name

1-[(1-ethyl-1H-imidazol-4-yl)sulfonyl]-N-(4-methylpyridin-2-yl)piperidine-3-carboxamide

SMILES

CCn1cnc(S(N(CCC2)CC2C(Nc2nccc(C)c2)=O)(=O)=O)c1

InChI

InChI=1S/C17H23N5O3S/c1-3-21-11-16(19-12-21)26(24,25)22-8-4-5-14(10-22)17(23)20-15-9-13(2)6-7-18-15/h6-7,9,11-12,14H,3-5,8,10H2,1-2H3,(H,18,20,23)/t14-/m0/s1

InChI Key

NGYDLGFFTUSZKW-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27139106

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.47

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.033

Distribution Coefficient, logD

1.030

Water Solubility, LogSw

-2.34

Polar Surface Area

76.423

Acid Dissociation Constant (pKa)

9.73

Base Dissociation Constant (pKb)

4.63

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

47.10

G404-2445 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Others
  • Kinases

References: we are preparing a list of scientific research reports with G404-2445 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G404-2445?
Check Price and Availability of G404-2445, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G404-2445 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G404-2445
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G404-2445
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G404-2445 available by request