G414-0351 Screening compound: N6-(3-methoxyphenyl)-1-methyl-N4-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

G414-0351 Screening compound: N6-(3-methoxyphenyl)-1-methyl-N4-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
G414-0351 Screening compound: N6-(3-methoxyphenyl)-1-methyl-N4-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound G414-0351
N6-(3-methoxyphenyl)-1-methyl-N4-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G414-0351

Molecular Formula

C20H20N6O (C20 H20 N6 O)

Compound Name

N6-(3-methoxyphenyl)-1-methyl-N4-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

IUPAC name

N6-(3-methoxyphenyl)-1-methyl-N4-(4-methylphenyl)-1H-pyrazolo[34-d]pyrimidine-46-diamine

SMILES

Cc(cc1)ccc1Nc1c(cnn2C)c2nc(Nc2cccc(OC)c2)n1

InChI

InChI=1S/C20H20N6O/c1-13-7-9-14(10-8-13)22-18-17-12-21-26(2)19(17)25-20(24-18)23-15-5-4-6-16(11-15)27-3/h4-12H,1-3H3,(H2,22,23,24,25)

InChI Key

PKLLXFWOGTZAJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27139867

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.785

Distribution Coefficient, logD

4.762

Water Solubility, LogSw

-4.52

Polar Surface Area

60.801

Acid Dissociation Constant (pKa)

17.88

Base Dissociation Constant (pKb)

6.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

G414-0351 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with G414-0351 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G414-0351?
Check Price and Availability of G414-0351, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G414-0351 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G414-0351
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G414-0351
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G414-0351 available by request