G416-0018 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-fluorobenzene-1-sulfonamide

G416-0018 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-fluorobenzene-1-sulfonamide
G416-0018 Screening compound: N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-fluorobenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G416-0018
N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-fluorobenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G416-0018

Molecular Formula

C23H23FN4O3S (C23 H23 FN4 O3 S)

Compound Name

N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-fluorobenzene-1-sulfonamide

IUPAC name

N-[5-(4-benzylpiperazine-1-carbonyl)pyridin-3-yl]-4-fluorobenzene-1-sulfonamide

SMILES

O=C(c1cc(NS(c(cc2)ccc2F)(=O)=O)cnc1)N1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C23H23FN4O3S/c24-20-6-8-22(9-7-20)32(30,31)26-21-14-19(15-25-16-21)23(29)28-12-10-27(11-13-28)17-18-4-2-1-3-5-18/h1-9,14-16,26H,10-13,17H2

InChI Key

GVZZPUYRYMXHDS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15011497

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.639

Distribution Coefficient, logD

2.574

Water Solubility, LogSw

-3.12

Polar Surface Area

70.684

Acid Dissociation Constant (pKa)

8.32

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

G416-0018 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with G416-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G416-0018?
Check Price and Availability of G416-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G416-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G416-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G416-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G416-0018 available by request