G418-0187 Screening compound: N-(4-{[(4-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]sulfamoyl}phenyl)acetamide

G418-0187 Screening compound: N-(4-{[(4-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]sulfamoyl}phenyl)acetamide
G418-0187 Screening compound: N-(4-{[(4-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]sulfamoyl}phenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G418-0187
N-(4-{[(4-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]sulfamoyl}phenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G418-0187

Molecular Formula

C23H19ClN4O4S (C23 H19 ClN4 O4 S)

Compound Name

N-(4-{[(4-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]sulfamoyl}phenyl)acetamide

IUPAC name

N-(4-{[(4-chlorophenyl)(5-phenyl-134-oxadiazol-2-yl)methyl]sulfamoyl}phenyl)acetamide

SMILES

CC(Nc(cc1)ccc1S(NC(c1nnc(-c2ccccc2)o1)c(cc1)ccc1Cl)(=O)=O)=O

InChI

InChI=1S/C23H19ClN4O4S/c1-15(29)25-19-11-13-20(14-12-19)33(30,31)28-21(16-7-9-18(24)10-8-16)23-27-26-22(32-23)17-5-3-2-4-6-17/h2-14,21,28H,1H3,(H,25,29)/t21-/m1/s1

InChI Key

FNMOMSMNFVIALR-OAQYLSRUSA-N

MDL Number (MFCD)

MFCD15011650

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.95

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.947

Distribution Coefficient, logD

3.558

Water Solubility, LogSw

-4.64

Polar Surface Area

95.068

Acid Dissociation Constant (pKa)

7.24

Base Dissociation Constant (pKb)

-1.73

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

8.70

G418-0187 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with G418-0187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G418-0187?
Check Price and Availability of G418-0187, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G418-0187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G418-0187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G418-0187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G418-0187 available by request