G423-0376 Screening compound: 7-(3,4-difluorophenyl)-3-{4-oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one

G423-0376 Screening compound: 7-(3,4-difluorophenyl)-3-{4-oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one
G423-0376 Screening compound: 7-(3,4-difluorophenyl)-3-{4-oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G423-0376
7-(3,4-difluorophenyl)-3-{4-oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G423-0376

Molecular Formula

C24H23F2N7O2 (C24 H23 F2 N7 O2)

Compound Name

7-(3,4-difluorophenyl)-3-{4-oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one

IUPAC name

7-(34-difluorophenyl)-3-{4-oxo-4-[4-(pyridin-2-yl)piperazin-1-yl]butyl}-7H8H-[124]triazolo[43-a]pyrazin-8-one

SMILES

O=C(CCCc1nnc2n1C=CN(c(cc1)cc(F)c1F)C2=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C24H23F2N7O2/c25-18-8-7-17(16-19(18)26)32-14-15-33-21(28-29-23(33)24(32)35)5-3-6-22(34)31-12-10-30(11-13-31)20-4-1-2-9-27-20/h1-2,4,7-9,14-16H,3,5-6,10-13H2

InChI Key

YYAWAHXMVIMGTK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140566

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.300

Distribution Coefficient, logD

1.291

Water Solubility, LogSw

-1.69

Polar Surface Area

67.261

Acid Dissociation Constant (pKa)

23.66

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

G423-0376 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G423-0376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G423-0376?
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What is the minimum amount of G423-0376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G423-0376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G423-0376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G423-0376 available by request