G430-1653 Screening compound: 1-{1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}-4-phenylpiperazine

G430-1653 Screening compound: 1-{1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}-4-phenylpiperazine
G430-1653 Screening compound: 1-{1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G430-1653
1-{1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G430-1653

Molecular Formula

C30H34N6O (C30 H34 N6 O)

Compound Name

1-{1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}-4-phenylpiperazine

IUPAC name

1-{1-[2-(34-dimethylphenyl)pyrazolo[15-a]pyrazin-4-yl]piperidine-3-carbonyl}-4-phenylpiperazine

SMILES

Cc(cc1)c(C)cc1-c1nn(ccnc2N(CCC3)CC3C(N(CC3)CCN3c3ccccc3)=O)c2c1

InChI

InChI=1S/C30H34N6O/c1-22-10-11-24(19-23(22)2)27-20-28-29(31-12-14-36(28)32-27)35-13-6-7-25(21-35)30(37)34-17-15-33(16-18-34)26-8-4-3-5-9-26/h3-5,8-12,14,19-20,25H,6-7,13,15-18,21H2,1-2H3/t25-/m0/s1

InChI Key

DQVIGFMIWHTYIN-VWLOTQADSA-N

MDL Number (MFCD)

MFCD27141137

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.64

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.948

Distribution Coefficient, logD

4.945

Water Solubility, LogSw

-4.68

Polar Surface Area

43.117

Acid Dissociation Constant (pKa)

22.67

Base Dissociation Constant (pKb)

5.23

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.70

G430-1653 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G430-1653 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G430-1653?
Check Price and Availability of G430-1653, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G430-1653 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G430-1653
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G430-1653
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G430-1653 available by request