G430-2301 Screening compound: 4-{1-[2-(3-chlorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}thiomorpholine

G430-2301 Screening compound: 4-{1-[2-(3-chlorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}thiomorpholine
G430-2301 Screening compound: 4-{1-[2-(3-chlorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}thiomorpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound G430-2301
4-{1-[2-(3-chlorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}thiomorpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G430-2301

Molecular Formula

C22H24ClN5OS (C22 H24 ClN5 OS)

Compound Name

4-{1-[2-(3-chlorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carbonyl}thiomorpholine

IUPAC name

4-{1-[2-(3-chlorophenyl)pyrazolo[15-a]pyrazin-4-yl]piperidine-3-carbonyl}thiomorpholine

SMILES

O=C(C(CCC1)CN1c(c1c2)nccn1nc2-c1cccc(Cl)c1)N1CCSCC1

InChI

InChI=1S/C22H24ClN5OS/c23-18-5-1-3-16(13-18)19-14-20-21(24-6-8-28(20)25-19)27-7-2-4-17(15-27)22(29)26-9-11-30-12-10-26/h1,3,5-6,8,13-14,17H,2,4,7,9-12,15H2/t17-/m0/s1

InChI Key

HBHHPYMVWMVDDQ-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27141156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.98

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.414

Distribution Coefficient, logD

3.411

Water Solubility, LogSw

-3.68

Polar Surface Area

39.856

Acid Dissociation Constant (pKa)

22.67

Base Dissociation Constant (pKb)

5.22

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.90

G430-2301 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G430-2301 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G430-2301?
Check Price and Availability of G430-2301, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G430-2301 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G430-2301
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G430-2301
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G430-2301 available by request