G435-0899 Screening compound: 1-[2-(4-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

G435-0899 Screening compound: 1-[2-(4-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide
G435-0899 Screening compound: 1-[2-(4-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-0899
1-[2-(4-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-0899

Molecular Formula

C28H32N6O2 (C28 H32 N6 O2)

Compound Name

1-[2-(4-butoxyphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

IUPAC name

1-[2-(4-butoxyphenyl)pyrazolo[15-a]pyrazin-4-yl]-N-[(pyridin-2-yl)methyl]piperidine-4-carboxamide

SMILES

CCCCOc(cc1)ccc1-c1nn(ccnc2N(CC3)CCC3C(NCc3ncccc3)=O)c2c1

InChI

InChI=1S/C28H32N6O2/c1-2-3-18-36-24-9-7-21(8-10-24)25-19-26-27(30-14-17-34(26)32-25)33-15-11-22(12-16-33)28(35)31-20-23-6-4-5-13-29-23/h4-10,13-14,17,19,22H,2-3,11-12,15-16,18,20H2,1H3,(H,31,35)

InChI Key

CDUJCNYAKWIRDP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142190

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.269

Distribution Coefficient, logD

4.267

Water Solubility, LogSw

-4.05

Polar Surface Area

64.649

Acid Dissociation Constant (pKa)

12.37

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.70

G435-0899 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases

References: we are preparing a list of scientific research reports with G435-0899 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-0899?
Check Price and Availability of G435-0899, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G435-0899 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-0899
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-0899
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-0899 available by request