G497-0002 Screening compound: N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2,4-dimethyl-1-benzenesulfonamide

G497-0002 Screening compound: N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2,4-dimethyl-1-benzenesulfonamide
G497-0002 Screening compound: N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2,4-dimethyl-1-benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G497-0002
N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2,4-dimethyl-1-benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G497-0002

Molecular Formula

C17H20N2O4S2 (C17 H20 N2 O4 S2)

Compound Name

N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2,4-dimethyl-1-benzenesulfonamide

IUPAC name

N-[4-(11-dioxo-1lambda62-thiazolidin-2-yl)phenyl]-24-dimethylbenzene-1-sulfonamide

SMILES

Cc(cc1)cc(C)c1S(Nc(cc1)ccc1N(CCC1)S1(=O)=O)(=O)=O

InChI

InChI=1S/C17H20N2O4S2/c1-13-4-9-17(14(2)12-13)25(22,23)18-15-5-7-16(8-6-15)19-10-3-11-24(19,20)21/h4-9,12,18H,3,10-11H2,1-2H3

InChI Key

LCNGHXPTHDXUQA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08003883

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.818

Distribution Coefficient, logD

2.574

Water Solubility, LogSw

-3.25

Polar Surface Area

72.924

Acid Dissociation Constant (pKa)

7.52

Base Dissociation Constant (pKb)

-7.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

G497-0002 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with G497-0002 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G497-0002?
Check Price and Availability of G497-0002, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G497-0002 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G497-0002
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G497-0002
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G497-0002 available by request