G497-0191 Screening compound: N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-4-isopropoxybenzamide

G497-0191 Screening compound: N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-4-isopropoxybenzamide
G497-0191 Screening compound: N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-4-isopropoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G497-0191
N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-4-isopropoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G497-0191

Molecular Formula

C19H22N2O4S (C19 H22 N2 O4 S)

Compound Name

N~1~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-4-isopropoxybenzamide

IUPAC name

N-[4-(11-dioxo-1lambda62-thiazolidin-2-yl)phenyl]-4-(propan-2-yloxy)benzamide

SMILES

CC(C)Oc(cc1)ccc1C(Nc(cc1)ccc1N(CCC1)S1(=O)=O)=O

InChI

InChI=1S/C19H22N2O4S/c1-14(2)25-18-10-4-15(5-11-18)19(22)20-16-6-8-17(9-7-16)21-12-3-13-26(21,23)24/h4-11,14H,3,12-13H2,1-2H3,(H,20,22)

InChI Key

ABAXWDDHWBRDQH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08004072

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.660

Distribution Coefficient, logD

2.660

Water Solubility, LogSw

-3.29

Polar Surface Area

62.168

Acid Dissociation Constant (pKa)

10.93

Base Dissociation Constant (pKb)

-0.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

G497-0191 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with G497-0191 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G497-0191?
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What is the minimum amount of G497-0191 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G497-0191
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G497-0191
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G497-0191 available by request