G497-0211 Screening compound: N~3~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2-oxo-2H-chromene-3-carboxamide

G497-0211 Screening compound: N~3~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2-oxo-2H-chromene-3-carboxamide
G497-0211 Screening compound: N~3~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2-oxo-2H-chromene-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G497-0211
N~3~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2-oxo-2H-chromene-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G497-0211

Molecular Formula

C19H16N2O5S (C19 H16 N2 O5 S)

Compound Name

N~3~-[4-(1,1-dioxotetrahydro-2H-1lambda~6~-isothiazol-2-yl)phenyl]-2-oxo-2H-chromene-3-carboxamide

IUPAC name

N-[4-(11-dioxo-1lambda62-thiazolidin-2-yl)phenyl]-2-oxo-2H-chromene-3-carboxamide

SMILES

O=C(C1=Cc(cccc2)c2OC1=O)Nc(cc1)ccc1N(CCC1)S1(=O)=O

InChI

InChI=1S/C19H16N2O5S/c22-18(16-12-13-4-1-2-5-17(13)26-19(16)23)20-14-6-8-15(9-7-14)21-10-3-11-27(21,24)25/h1-2,4-9,12H,3,10-11H2,(H,20,22)

InChI Key

DRQSLFVQMVBILG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08004092

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.41

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.850

Distribution Coefficient, logD

1.845

Water Solubility, LogSw

-2.52

Polar Surface Area

76.287

Acid Dissociation Constant (pKa)

9.32

Base Dissociation Constant (pKb)

0.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

G497-0211 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with G497-0211 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G497-0211?
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What is the minimum amount of G497-0211 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G497-0211
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G497-0211
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G497-0211 available by request