G500-0358 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-3,4,5-trimethoxybenzamide

G500-0358 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-3,4,5-trimethoxybenzamide
G500-0358 Screening compound: N-{2-[4-(dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-3,4,5-trimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G500-0358
N-{2-[4-(dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-3,4,5-trimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G500-0358

Molecular Formula

C25H36N4O4 (C25 H36 N4 O4)

Compound Name

N-{2-[4-(dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-3,4,5-trimethoxybenzamide

IUPAC name

N-{2-[4-(dimethylamino)phenyl]-2-(4-methylpiperazin-1-yl)ethyl}-345-trimethoxybenzamide

SMILES

CN(C)c1ccc(C(CNC(c(cc2OC)cc(OC)c2OC)=O)N2CCN(C)CC2)cc1

InChI

InChI=1S/C25H36N4O4/c1-27(2)20-9-7-18(8-10-20)21(29-13-11-28(3)12-14-29)17-26-25(30)19-15-22(31-4)24(33-6)23(16-19)32-5/h7-10,15-16,21H,11-14,17H2,1-6H3,(H,26,30)/t21-/m0/s1

InChI Key

AMSQYYKAWFXTJC-NRFANRHFSA-N

MDL Number (MFCD)

MFCD08005167

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.208

Distribution Coefficient, logD

1.835

Water Solubility, LogSw

-3.09

Polar Surface Area

56.900

Acid Dissociation Constant (pKa)

13.27

Base Dissociation Constant (pKb)

7.53

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

48.00

G500-0358 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G500-0358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G500-0358?
Check Price and Availability of G500-0358, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G500-0358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G500-0358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G500-0358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G500-0358 available by request