G516-0154 Screening compound: 2-(4-methoxyphenyl)-N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}quinazolin-4-amine

G516-0154 Screening compound: 2-(4-methoxyphenyl)-N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}quinazolin-4-amine
G516-0154 Screening compound: 2-(4-methoxyphenyl)-N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}quinazolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G516-0154
2-(4-methoxyphenyl)-N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}quinazolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G516-0154

Molecular Formula

C28H31N5O2 (C28 H31 N5 O2)

Compound Name

2-(4-methoxyphenyl)-N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}quinazolin-4-amine

IUPAC name

2-(4-methoxyphenyl)-N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}quinazolin-4-amine

SMILES

COc(cc1)ccc1-c1nc2ccccc2c(NCCN(CC2)CCN2c(cc2)ccc2OC)n1

InChI

InChI=1S/C28H31N5O2/c1-34-23-11-7-21(8-12-23)27-30-26-6-4-3-5-25(26)28(31-27)29-15-16-32-17-19-33(20-18-32)22-9-13-24(35-2)14-10-22/h3-14H,15-20H2,1-2H3,(H,29,30,31)

InChI Key

DWGUANVNSLIYHX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15015037

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.903

Distribution Coefficient, logD

5.719

Water Solubility, LogSw

-5.94

Polar Surface Area

51.299

Acid Dissociation Constant (pKa)

18.40

Base Dissociation Constant (pKb)

7.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

G516-0154 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G516-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G516-0154?
Check Price and Availability of G516-0154, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G516-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G516-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G516-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G516-0154 available by request