G543-1056 Screening compound: 1-{1-[(4-chlorophenyl)methyl]-1H-imidazole-2-carbonyl}-4-(furan-2-carbonyl)piperazine

G543-1056 Screening compound: 1-{1-[(4-chlorophenyl)methyl]-1H-imidazole-2-carbonyl}-4-(furan-2-carbonyl)piperazine
G543-1056 Screening compound: 1-{1-[(4-chlorophenyl)methyl]-1H-imidazole-2-carbonyl}-4-(furan-2-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G543-1056
1-{1-[(4-chlorophenyl)methyl]-1H-imidazole-2-carbonyl}-4-(furan-2-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G543-1056

Molecular Formula

C20H19ClN4O3 (C20 H19 ClN4 O3)

Compound Name

1-{1-[(4-chlorophenyl)methyl]-1H-imidazole-2-carbonyl}-4-(furan-2-carbonyl)piperazine

IUPAC name

1-{1-[(4-chlorophenyl)methyl]-1H-imidazole-2-carbonyl}-4-(furan-2-carbonyl)piperazine

SMILES

O=C(c1ccco1)N(CC1)CCN1C(c1nccn1Cc(cc1)ccc1Cl)=O

InChI

InChI=1S/C20H19ClN4O3/c21-16-5-3-15(4-6-16)14-25-8-7-22-18(25)20(27)24-11-9-23(10-12-24)19(26)17-2-1-13-28-17/h1-8,13H,9-12,14H2

InChI Key

FBMOPNKVNXSJEM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15017882

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.85

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.953

Distribution Coefficient, logD

1.953

Water Solubility, LogSw

-2.45

Polar Surface Area

53.431

Acid Dissociation Constant (pKa)

21.68

Base Dissociation Constant (pKb)

1.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G543-1056 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

GPCR Targeted Library (31838 compounds)

Ion Channels Focused Library (26372 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G543-1056 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G543-1056?
Check Price and Availability of G543-1056, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G543-1056 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G543-1056
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G543-1056
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G543-1056 available by request