G574-0466 Screening compound: N'-(3-acetamidophenyl)-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}ethanediamide

G574-0466 Screening compound: N'-(3-acetamidophenyl)-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}ethanediamide
G574-0466 Screening compound: N'-(3-acetamidophenyl)-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}ethanediamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G574-0466
N'-(3-acetamidophenyl)-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}ethanediamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G574-0466

Molecular Formula

C22H19FN6O3S (C22 H19 FN6 O3 S)

Compound Name

N'-(3-acetamidophenyl)-N-{2-[2-(3-fluorophenyl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-yl]ethyl}ethanediamide

IUPAC name

N'-(3-acetamidophenyl)-N-{2-[2-(3-fluorophenyl)-[124]triazolo[32-b][13]thiazol-6-yl]ethyl}ethanediamide

SMILES

CC(Nc1cccc(NC(C(NCCc2csc3nc(-c4cc(F)ccc4)nn23)=O)=O)c1)=O

InChI

InChI=1S/C22H19FN6O3S/c1-13(30)25-16-6-3-7-17(11-16)26-21(32)20(31)24-9-8-18-12-33-22-27-19(28-29(18)22)14-4-2-5-15(23)10-14/h2-7,10-12H,8-9H2,1H3,(H,24,31)(H,25,30)(H,26,32)

InChI Key

BBCZIOBZECFFQO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08318458

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.346

Distribution Coefficient, logD

2.321

Water Solubility, LogSw

-2.96

Polar Surface Area

92.322

Acid Dissociation Constant (pKa)

8.63

Base Dissociation Constant (pKb)

0.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

G574-0466 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G574-0466 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G574-0466?
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What is the minimum amount of G574-0466 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G574-0466
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G574-0466
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G574-0466 available by request