G581-0035 Screening compound: 4-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-(1-methyl-1H-indol-3-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

G581-0035 Screening compound: 4-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-(1-methyl-1H-indol-3-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one
G581-0035 Screening compound: 4-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-(1-methyl-1H-indol-3-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G581-0035
4-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-(1-methyl-1H-indol-3-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G581-0035

Molecular Formula

C27H27FN6O2 (C27 H27 FN6 O2)

Compound Name

4-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-(1-methyl-1H-indol-3-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidin-5-one

IUPAC name

4-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-(1-methyl-1H-indol-3-yl)-4H5H6H7H-pyrazolo[15-a]pyrimidin-5-one

SMILES

Cn1c(cccc2)c2c(-c2nn(CCC(N3CC(N(CC4)CCN4c(cccc4)c4F)=O)=O)c3c2)c1

InChI

InChI=1S/C27H27FN6O2/c1-30-17-20(19-6-2-4-8-23(19)30)22-16-25-33(26(35)10-11-34(25)29-22)18-27(36)32-14-12-31(13-15-32)24-9-5-3-7-21(24)28/h2-9,16-17H,10-15,18H2,1H3

InChI Key

FBHSHHYBABMULF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15020490

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.041

Distribution Coefficient, logD

3.041

Water Solubility, LogSw

-3.35

Polar Surface Area

49.932

Acid Dissociation Constant (pKa)

22.08

Base Dissociation Constant (pKb)

4.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.60

G581-0035 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G581-0035 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G581-0035?
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What is the minimum amount of G581-0035 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G581-0035
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G581-0035
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G581-0035 available by request